Prediction of Fetal Anemia by Middle Cerebral Artery Peak Systolic Velocity in Pregnancies Complicated by Rhesus Isoimmunization

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Prediction of fetal anemia in rhesus disease by measurement of fetal middle cerebral artery peak systolic velocity.

OBJECTIVE In red blood cell (RBC) isoimmunized pregnancies fetal anemia is associated with a hyperdynamic circulation. The aim of the present study was to examine further the possible value of fetal middle cerebral artery peak systolic velocity (MCA-PSV) in the management of affected pregnancies. METHODS A reference range of fetal MCA-PSV with gestation was constructed from the study of 813 n...

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Middle cerebral artery peak systolic velocity for the diagnosis of fetal anemia: the untold story.

The use of the middle cerebral artery peak systolic velocity (MCA-PSV) for the diagnosis of fetal anemia has been one of the few discoveries in fetal medicine that is changing the standard of care in the management of affected pregnancies1. This has led to a more than 70% reduction in the number of invasive tests, which often cause fetal death, in the assessment of red-cell alloimmunized pregna...

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A Study of Fetal Middle Cerebral Artery Peak Systolic Velocity to Diagnose Fetal Anemia in Rural Obstetric Population

Globally, fetal middle cerebral artery peak systolic velocity (MCA-PSV) is used for noninvasive diagnosis of fetal anemia. Although, incidence of anemia is common in rural setup, scientific studies describing utilization of this modality are lacking. This study throws light on how the use of fetal MCAPSV to diagnose fetal anemia can help in the decision-making process even in a rural setup. Con...

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The value of reference ranges for middle cerebral artery peak systolic velocity in the management of rhesus alloimmunized pregnancies.

OBJECTIVES To establish reference ranges for middle cerebral artery peak systolic velocity (MCA PSV) and to certify their value in the management of Rhesus alloimmunized pregnancies. MATERIAL AND METHODS A reference range of MCA PSV with gestation was constructed by studying 342 pregnancies at 25-40 weeks. A comparison was made between the reference ranges produced in our study and those alre...

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Middle cerebral artery peak systolic velocity: technique and variability.

OBJECTIVE Assessment of the middle cerebral artery (MCA) peak systolic velocity (PSV) can accurately diagnose fetal anemia and has decreased the number of invasive procedures, such as amniocentesis and cordocentesis. The objective of this investigation was to evaluate the intraobserver and interobserver variability as a measure of reproducibility of MCA PSV. The technique of correctly sampling ...

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ژورنال

عنوان ژورنال: Journal of Perinatology

سال: 2003

ISSN: 0743-8346,1476-5543

DOI: 10.1038/sj.jp.7210979